Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329587 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL8330062 | 0.84 | TSHR (0.48) | ALDH1A1TSHRL3MBTL1NPSR1KMT2A | |
| SCHEMBL24869876 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL6081935 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL8329591 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL21834562 | 0.72 | L3MBTL1 (0.51) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL1565359 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL31547177 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TSHRL3MBTL1NPSR1LMNA | |
| SCHEMBL2328825 | 0.71 | USP2 (0.38) | ALDH1A1RECQL | |
| SCHEMBL8330052 | 0.70 | TSHR (0.43) | ALDH1A1TSHRL3MBTL1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |