SCHEMBL83296

SCHEMBL83296

CCCC[SiH](CCCC)C1CCCCO1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5183836 0.94 EPHX1 (0.37) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL21522637 0.93 EPHX1 (0.40) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL29233375 0.93 EPHX1 (0.40) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL20240978 0.93 EPHX1 (0.40) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL7102818 0.93 EPHX1 (0.40) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL29233372 0.93 EPHX1 (0.40) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL51769 0.88
SCHEMBL4929388 0.83 CYP1A2 (0.36) EPHX1CYP1A2ALDH1A1TDP1
SCHEMBL20535377 0.81
SCHEMBL4432862 0.81 SIGMAR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667780-B2 Impact modified styrene copolymer composition comprising polysiloxane additive having improved abrasion characteristics INEOS STYROLUTION GROUP GMBH (DE) 2023-06-06 US claimed
CN-111247205-A Impact modified styrenic copolymer compositions containing polysiloxane additives with improved abrasion resistance 英力士苯领集团股份公司 2020-06-05 CN claimed
EP-3658623-A1 IMPACT MODIFIED STYRENE COPOLYMER COMPOSITION COMPRISING POLYSILOXANE ADDITIVE HAVING IMPROVED ABRASION CHARACTERISTICS INEOS Styrolution Group GmbH (DE) 2020-06-03 EP claimed
US-20200148872-A1 IMPACT MODIFIED STYRENE COPOLYMER COMPOSITION COMPRISING POLYSILOXANE ADDITIVE HAVING IMPROVED ABRASION CHARACTERISTICS HSBC CORPORATE TRUSTEE COMPANY (UK) LIMITED (GB) 2020-05-14 US claimed
WO-2019020677-A1 IMPACT MODIFIED STYRENE COPOLYMER COMPOSITION COMPRISING POLYSILOXANE ADDITIVE HAVING IMPROVED ABRASION CHARACTERISTICS INEOS STYROLUTION GROUP GMBH (DE) 2019-01-31 WO claimed
WO-2018104079-A1 PIPE PRODUCED WITH A POLYMER COMPOSITION COMPRISING A POLYOLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-14 WO claimed
US-9771495-B2 Low temperature segmented copolymer compositions and methods THE BOEING COMPANY (US) 2017-09-26 US claimed
US-20160312066-A1 LOW TEMPERATURE SEGMENTED COPOLYMER COMPOSITIONS AND METHODS THE BOEING COMPANY 2016-10-27 US claimed
US-9388272-B2 Low temperature segmented copolymer compositions and methods THE BOEING COMPANY (US) 2016-07-12 US claimed
US-20150133602-A1 LOW TEMPERATURE SEGMENTED COPOLYMER COMPOSITIONS AND METHODS THE BOEING COMPANY 2015-05-14 US claimed
EP-2601245-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF Biofilm IP, LLC (US) 2013-06-12 EP claimed
US-8334356-B1 Low temperature segmented copolymer compositions and methods THE BOEING COMPANY (US) 2012-12-18 US claimed
US-20120128874-A1 LUBRICIOUS COATINGS TYCO HEALTHCARE GROUP LP 2012-05-24 US claimed
US-20120064022-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM, INC. 2012-03-15 US claimed
US-8128599-B2 Lubricious coatings TYCO HEALTHCARE GROUP LP (US) 2012-03-06 US claimed
WO-2012018403-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM IP, LLC (US) 2012-02-09 WO claimed
US-20090024097-A1 LUBRICIOUS COATINGS TYCO HEALTHCARE GROUP LP 2009-01-22 US claimed
EP-2016972-A2 Lubricious coatings Tyco Healthcare Group LP (US) 2009-01-21 EP claimed
EP-1813295-A2 Coated surgical needles TYCO HEALTHCARE GROUP LP (US) 2007-08-01 EP claimed
US-5527484-A A MIXTURE OF PROTEASE AND AMYLASE ENZYMES COLGATE-PALMOLIVE CO. (US) 1996-06-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120064022-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF PIEZO1, DSC1, PFAS EPHX1 2029/4885CYP1A2 4097/4885ALDH1A1 4496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.