SCHEMBL4432862

SCHEMBL4432862

NCCC[SiH](CCCN)C1CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28246435 0.96
SCHEMBL28067011 0.90
SCHEMBL516195 0.81 SIGMAR1 (0.33) SIGMAR1
SCHEMBL20535408 0.81
SCHEMBL20535377 0.81
SCHEMBL20535235 0.81
SCHEMBL83296 0.81 EPHX1 (0.34)
SCHEMBL16499606 0.81 MAOA (0.33) SIGMAR1
SCHEMBL5183836 0.79 EPHX1 (0.37)
SCHEMBL21522637 0.78 EPHX1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134726-A1 IMPROVED PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES Momentive Performance Materials Inc. (US) 2009-12-23 EP claimed
WO-2008115190-A1 IMPROVED PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-09-25 WO claimed
US-20080234441-A1 PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-25 US claimed
EP-4363488-B1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER DOW SILICONES CORP (US) 2025-04-16 EP disclosed
US-20240180813-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER DOW SILICONES CORP (US) 2024-06-06 US disclosed
EP-4363488-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER Dow Silicones Corporation (US) 2024-05-08 EP disclosed
WO-2023278918-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER DOW SILICONES CORPORATION (US) 2023-01-05 WO disclosed
EP-2134726-A1 IMPROVED PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES Momentive Performance Materials Inc. (US) 2009-12-23 EP disclosed
WO-2008115190-A1 IMPROVED PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-09-25 WO disclosed
US-20080234441-A1 PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-25 US disclosed
EP-0647886-B1 Polyesteramide-siloxane toner and developer compositions XEROX CORP (US) 2000-02-23 EP disclosed
EP-0647886-A1 Polyesteramide-siloxane toner and developer compositions XEROX CORPORATION (US) 1995-04-12 EP disclosed
US-5401601-A Polyesteramide-siloxane toner and developer compositions XEROX CORPORATION (US) 1995-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180813-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER POLR1C, SUCLG1, SRM SIGMAR1 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.