Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965010 | 0.90 | HCRTR1 (0.33) | DHODHHCRTR1HCRTR2FAAHALDH1A1 | |
| SCHEMBL7952522 | 0.90 | ALDH1A1 (0.35) | DHODHSMN1; SMN2LMNAHCRTR1HCRTR2 | |
| SCHEMBL8330821 | 0.89 | DHODH (0.36) | DHODHMALT1 | |
| SCHEMBL7962103 | 0.87 | MEN1 (0.35) | SMN1; SMN2LMNAKMT2AALDH1A1CYP2C19 | |
| SCHEMBL8329371 | 0.86 | DPP4 (0.35) | DHODHSMN1; SMN2LMNAHCRTR1HCRTR2 | |
| SCHEMBL8328923 | 0.86 | DHODH (0.37) | DHODHSMN1; SMN2LMNAHCRTR1HCRTR2 | |
| SCHEMBL8326401 | 0.85 | DHODH (0.37) | DHODHSMN1; SMN2LMNAHCRTR1HCRTR2 | |
| SCHEMBL7965374 | 0.83 | DHODH (0.36) | DHODHHCRTR1HCRTR2FAAHALDH1A1 | |
| SCHEMBL7961792 | 0.82 | DHODH (0.36) | DHODHHCRTR1HCRTR2FAAHALDH1A1 | |
| SCHEMBL7961108 | 0.80 | DHODH (0.35) | DHODHSMN1; SMN2LMNAHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |