Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961108 | 0.91 | DHODH (0.35) | MEN1KMT2AALDH1A1IDO1LMNA | |
| SCHEMBL7964731 | 0.90 | FPR1 (0.35) | MEN1KMT2AALDH1A1IDO1LMNA | |
| SCHEMBL7962570 | 0.90 | CDK5 (0.34) | MEN1KMT2AALDH1A1IDO1LMNA | |
| SCHEMBL7961198 | 0.89 | MEN1 (0.34) | MEN1KMT2AALDH1A1IDO1LMNA | |
| SCHEMBL7965010 | 0.89 | HCRTR1 (0.33) | ALDH1A1CYP2C19PDE4B | |
| SCHEMBL7963301 | 0.88 | HCRTR1 (0.34) | MEN1KMT2AALDH1A1IDO1CYP2C19 | |
| SCHEMBL7963885 | 0.88 | KCNMA1 (0.36) | MEN1KMT2AALDH1A1IDO1LMNA | |
| SCHEMBL8330160 | 0.87 | DHODH (0.38) | KMT2AALDH1A1LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL7952522 | 0.86 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7961656 | 0.83 | FAAH (0.34) | ALDH1A1MAPTCYP2C19CDK5DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |