Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965050 | 0.92 | CYP2C19 (0.33) | DHODHFAAHCYP2C19HCRTR1HCRTR2 | |
| SCHEMBL7961198 | 0.91 | MEN1 (0.34) | CYP2C19LMNASMN1; SMN2KMT2AIDO1 | |
| SCHEMBL7962835 | 0.91 | ALDH1A1 (0.33) | DHODHFAAHCYP2C19HCRTR1HCRTR2 | |
| SCHEMBL8330797 | 0.90 | DHODH (0.36) | DHODHHCRTR1KMT2APER2 | |
| SCHEMBL8330160 | 0.85 | DHODH (0.38) | DHODHFAAHCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL7965681 | 0.82 | FPR1 (0.33) | DHODHHCRTR1PER2 | |
| SCHEMBL8328200 | 0.82 | CHRNB1 (0.35) | KMT2APOLBALDH1A1 | |
| SCHEMBL7961758 | 0.81 | FPR1 (0.35) | LMNASMN1; SMN2HCRTR1KMT2AIDO1 | |
| SCHEMBL7961641 | 0.81 | BACE1 (0.34) | DHODHHCRTR1PER2 | |
| SCHEMBL7961100 | 0.80 | DPP4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |