Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL9749355 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Didecyldimethylammonium SCHEMBL2370472 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL4142977 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL10738734 | 0.97 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL10823138 | 0.95 | DNM1 (0.53) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL10815854 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL21629461 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Cetrimonium SCHEMBL4841411 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL4841282 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL9814393 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955288-A2 | Dialkylquat and trialkylquat benzoate and salicylate salts | WITCO CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |