Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL315381 | 0.95 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL30754678 | 0.95 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Tributylmethylammonium SCHEMBL3468660 | 0.94 | KDM4E (0.58) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL9814393 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL8330264 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL10815854 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL9749355 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Didecyldimethylammonium SCHEMBL2370472 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL4841282 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Cetrimonium SCHEMBL4841411 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200030716-A1 | TASK SPECIFIC CHELATING IONIC LIQUIDS FOR REMOVAL OF METAL IONS FROM AQUEOUS SOLUTION VIA LIQUID/LIQUID EXTRACTION AND ELECTROCHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-01-30 | — | — | US | claimed |
| WO-2020023752-A1 | TASK SPECIFIC CHELATING IONIC LIQUIDS FOR REMOVAL OF METAL IONS FROM AQUEOUS SOLUTION VIA LIQUID/LIQUID EXTRACTION AND ELECTROCHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-01-30 | — | — | WO | claimed |
| US-20200030716-A1 | TASK SPECIFIC CHELATING IONIC LIQUIDS FOR REMOVAL OF METAL IONS FROM AQUEOUS SOLUTION VIA LIQUID/LIQUID EXTRACTION AND ELECTROCHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-01-30 | — | — | US | disclosed |
| WO-2020023752-A1 | TASK SPECIFIC CHELATING IONIC LIQUIDS FOR REMOVAL OF METAL IONS FROM AQUEOUS SOLUTION VIA LIQUID/LIQUID EXTRACTION AND ELECTROCHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030716-A1 | TASK SPECIFIC CHELATING IONIC LIQUIDS FOR REMOVAL OF METAL IONS FROM AQUEOUS SOLUTION VIA LIQUID/LIQUID EXTRACTION AND ELECTROCHEMISTRY | SOD1, SOD3, SLC39A11 | ALDH1A1 2586/4885KDM4E 3493/4885HPGD 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.