Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330635 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL7486384 | 0.71 | TDP1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL3328503 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRCA2 | |
| SCHEMBL8330089 | 0.69 | METAP2 (0.40) | ALDH1A1 | |
| SCHEMBL8331526 | 0.68 | ALDH1A1 (0.48) | ALDH1A1TSHR | |
| SCHEMBL2782792 | 0.66 | CA12 (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL8330628 | 0.66 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL9782826 | 0.65 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL8330632 | 0.65 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL27778239 | 0.64 | ALDH1A1 (0.38) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |