Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062152 | 0.92 | ALDH1A1 (0.56) | TDP1L3MBTL1CES1CDC25A | |
| SCHEMBL8008712 | 0.84 | MGLL (0.62) | TDP1L3MBTL1CES1CDC25A | |
| SCHEMBL8008707 | 0.84 | MGLL (0.62) | TDP1L3MBTL1CES1CDC25A | |
| SCHEMBL9626594 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL10725536 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL23731163 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL8862943 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL10731237 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL8863074 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL732925 | 0.83 | CES1 (0.68) | TDP1L3MBTL1CHRM2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958903-A | CHOLINESTERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-09-28 | — | — | US | disclosed |