SCHEMBL8331978

SCHEMBL8331978

CCCCC(N)(C(CP(=O)(O)O)CP(=O)(O)O)P(=O)(O)O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 12/20 0.53
SMPD1 P17405 4/20 0.46
GGPS1 O95749 5/20 0.40
LAP3 P28838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4734366 0.70 FDPS (1.00) FDPSSMPD1GGPS1
SCHEMBL466967 0.69 FDPS (0.56) FDPSSMPD1GGPS1LAP3
SCHEMBL8470467 0.69 FDPS (0.44) FDPSSMPD1LAP3
SCHEMBL2989901 0.68 FDPS (0.44) FDPSSMPD1LAP3
Phosphoric Acid SCHEMBL12816061 0.68 FDPS (0.64) FDPSSMPD1GGPS1
SCHEMBL6454040 0.67 LAP3 (0.39) FDPSSMPD1LAP3
SCHEMBL11334311 0.65 FDPS (0.60) FDPSSMPD1GGPS1
SCHEMBL8332966 0.65 GGPS1 (0.82) FDPSSMPD1GGPS1
Phosphoric Acid SCHEMBL8911229 0.65 FDPS (0.63) FDPSSMPD1GGPS1
SCHEMBL3414399 0.65 FDPS (1.00) FDPSSMPD1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802919-A4 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS MALLINCKRODT MEDICAL INC (US) 1999-08-18 EP disclosed
EP-0802919-A1 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS MALLINCKRODT MEDICAL, INC. (US) 1997-10-29 EP disclosed
WO-1995033757-A1 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS MALLINCKRODT MEDICAL, INC. (US) 1995-12-14 WO disclosed
US-4497744-A Gentisic acid salts as radiographic scanning agent stabilizers MALLINCKRODT, INC. (US) 1985-02-05 US disclosed
US-4330537-A PHOSPHONATE COMPOUNDS AND VITAMIN D DERIVATIVES USEFUL AGAINST OSTEOPORSIS THE PROCTER & GAMBLE COMPANY (US) 1982-05-18 US disclosed
EP-0006659-B1 COMPOSITIONS USEFUL IN THE PREPARATION OF STABILIZED RADIOGRAPHIC SCANNING AGENTS, A METHOD OF PREPARING THEM AND THE USE OF STANNOUS GENTISILATE AS STABILIZER IN THESE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1982-04-21 EP disclosed
EP-0004684-B1 STABILIZED RADIOGRAPHIC SCANNING AGENTS AND METHOD FOR PREPARING THEM THE PROCTER & GAMBLE COMPANY (US) 1981-09-16 EP disclosed
US-4234562-A WITH TECHNETIUM-99, A STANNOUS, FERROUS OR CHROMOUS CHLORIDE OR SULFATE, AN ORGANIC PHOSPHONIC ACID THE PROCTER & GAMBLE COMPANY (US) 1980-11-18 US disclosed
US-4233284-A GENESTIC ACID, SALT OR ESTER THEREOF IN COMBINATION WITH A PERTECHNETATE REDUCING AGENT BECOMES LOCALIZED IN SPECIFIC BODY ORGANS OR BONES THE PROCTER & GAMBLE COMPANY (US) 1980-11-11 US disclosed
US-4232000-A GENTISYL ALCOHOL, REDUCING AGENT THE PROCTER & GAMBLE COMPANY (US) 1980-11-04 US disclosed
US-4230700-A ADMINISTERING AN ORGANIC MONO- OR DIPHOSPHONATE AND A VITAMIN-D-LIKE ANTIRACHITIC COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1980-10-28 US disclosed
EP-0006659-A1 Compositions useful in the preparation of stabilized radiographic scanning agents, a method of preparing them and the use of stannous gentisilate as stabilizer in these compositions THE PROCTER & GAMBLE COMPANY (US) 1980-01-09 EP disclosed
EP-0004684-A2 Stabilized radiographic scanning agents and method for preparing them THE PROCTER & GAMBLE COMPANY (US) 1979-10-17 EP disclosed
US-3983227-A TECHNETIUM THE PROCTER & GAMBLE COMPANY (US) 1976-09-28 US disclosed
US-3965254-A Compositions for the treatment of calcific tumors THE PROCTER & GAMBLE COMPANY (US) 1976-06-22 US disclosed