SCHEMBL466967

SCHEMBL466967

CCCCCCCCCCCCCCCCC(O)C(N)(CCCCCCCCCCCCCCCC)P(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 12/20 0.56
SMPD1 P17405 4/20 0.56
GGPS1 O95749 6/20 0.50
LPAR1 Q92633 1/20 0.47
LPAR3 Q9UBY5 1/20 0.47
LAP3 P28838 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2131483 0.91 GGPS1 (0.48) FDPSSMPD1GGPS1
SCHEMBL6771978 0.79 FDPS (0.51) FDPSSMPD1LAP3
Phosphoric Acid SCHEMBL670802 0.79 LAP3 (0.53) FDPSSMPD1LAP3
Phosphoric Acid SCHEMBL2806140 0.79 LAP3 (0.53) FDPSSMPD1LAP3
Phosphoric Acid SCHEMBL4615576 0.77 LAP3 (0.52) FDPSSMPD1LAP3
SCHEMBL6767199 0.75 FDPS (0.50) FDPSSMPD1GGPS1LAP3
SCHEMBL28901725 0.74 GGPS1 (0.47) FDPSSMPD1GGPS1LPAR1LPAR3
SCHEMBL8858304 0.73 FDPS (0.48) FDPSSMPD1GGPS1LAP3
Hydrochloric Acid SCHEMBL9635702 0.73 SPHK1 (0.44) FDPSSMPD1GGPS1
Bromide SCHEMBL9716432 0.73 SPHK1 (0.44) FDPSSMPD1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11173119-B2 Nanolipogel vehicles for controlled delivery of different pharmaceutical agents YALE UNIVERSITY (US) 2021-11-16 US claimed
US-10709664-B2 Nanolipogel comprising a polymeric matrix and a lipid shell YALE UNIVERSITY (US) 2020-07-14 US claimed
US-20200179283-A1 Vehicles For Controlled Delivery of Different Pharmaceutical Agents NATIONAL SCIENCE FOUNDATION 2020-06-11 US claimed
US-20190209474-A1 METHODS OF TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES AND DISORDERS MODULATE THERAPEUTICS INC (CA) 2019-07-11 US claimed
EP-2836234-B1 VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS UNIV YALE (US) 2019-06-12 EP claimed
US-10195144-B2 Methods of treating inflammatory and autoimmune diseases and disorders YALE UNIVERSITY (US) 2019-02-05 US claimed
US-20170224617-A1 METHODS OF TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES AND DISORDERS MODULATE THERAPEUTICS INC (CA) 2017-08-10 US claimed
US-9610250-B2 Nanolipogel vehicles for controlled delivery of different pharmaceutical agents YALE UNIVERSITY (US) 2017-04-04 US claimed
US-9603800-B2 Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels YALE UNIVERSITY (US) 2017-03-28 US claimed
US-20150118318-A1 Methods of Treating Inflammatory and Autoimmune Diseases and Disorders YALE UNIVERSITY (US) 2015-04-30 US claimed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 EP claimed
US-20150064265-A1 Vehicles for Controlled Delivery of Different Pharmaceutical Agents YALE UNIVERSITY 2015-03-05 US claimed
WO-2024137455-A1 NANOPARTICULATE FORMULATION NEWIMMUNE II, LLC (US) 2024-06-27 WO disclosed
US-20240211771-A1 SEQUENCE-CONTROLLED POLYMER RANDOM ACCESS MEMORY STORAGE U.S. DEPARTMENT OF ENERGY 2024-06-27 US disclosed
US-11969396-B2 IPA-3-loaded liposomes and methods of use thereof UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-04-30 US disclosed
US-11961008-B2 Sequence-controlled polymer random access memory storage MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-04-16 US disclosed
WO-2009061003-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-05-14 WO disclosed
EP-1946761-A1 CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT Otsuka Pharmaceutical Co., Ltd. (JP) 2008-07-23 EP disclosed
EP-1920765-A1 Liposome preparation by single-pass process Medigene AG (DE) 2008-05-14 EP disclosed
EP-1915987-A1 Spray-freeze-drying process for the preparation of pellets comprising percolation drying MediGene AG (DE) 2008-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150064265-A1 Vehicles for Controlled Delivery of Different Pharmaceutical Agents CETP, HDLBP, ABCG2 FDPS 2720/4885SMPD1 1303/4885GGPS1 2595/4885
US-11173119-B2 Nanolipogel vehicles for controlled delivery of different pharmaceutical agents LIPA, ABCF1, ABCG2 FDPS 2796/4885SMPD1 1136/4885GGPS1 2708/4885
US-20190209474-A1 METHODS OF TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES AND DISORDERS UACA, HLA-DRB1, TNF FDPS 2545/4885SMPD1 749/4885GGPS1 1607/4885
US-20200179283-A1 Vehicles For Controlled Delivery of Different Pharmaceutical Agents CETP, HDLBP, ABCG2 FDPS 2720/4885SMPD1 1303/4885GGPS1 2595/4885
US-20170224617-A1 METHODS OF TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES AND DISORDERS UACA, HLA-DRB1, TNF FDPS 2545/4885SMPD1 749/4885GGPS1 1607/4885
US-11969396-B2 IPA-3-loaded liposomes and methods of use thereof PAK3, PAK1, PAK6 FDPS 2740/4885SMPD1 27/4885GGPS1 500/4885
US-10709664-B2 Nanolipogel comprising a polymeric matrix and a lipid shell LIPA, CD44, ABCB4 FDPS 2538/4885SMPD1 738/4885GGPS1 2123/4885
US-20150118318-A1 Methods of Treating Inflammatory and Autoimmune Diseases and Disorders UACA, HLA-DRB1, TNF FDPS 2545/4885SMPD1 749/4885GGPS1 1607/4885
US-10195144-B2 Methods of treating inflammatory and autoimmune diseases and disorders UACA, HLA-DRB1, LIPA FDPS 2576/4885SMPD1 737/4885GGPS1 1659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.