Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 3/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454040 | 0.71 | LAP3 (0.39) | FDPSGRM4GABBR2GABBR1LAP3 | |
| SCHEMBL2510795 | 0.70 | FDPS (0.52) | FDPSGRM4GABBR2GABBR1LMNA | |
| SCHEMBL9632822 | 0.70 | FDPS (0.46) | FDPSGRM4LMNALAP3SMPD1 | |
| SCHEMBL8331978 | 0.69 | FDPS (0.53) | FDPSLAP3SMPD1 | |
| SCHEMBL1048720 | 0.69 | FDPS (0.50) | FDPSGRM4GABBR2GABBR1LMNA | |
| SCHEMBL6777911 | 0.68 | FDPS (0.44) | FDPSGRM4GABBR2GABBR1LMNA | |
| SCHEMBL13186076 | 0.68 | GABBR2 (0.33) | FDPSGRM4GABBR2GABBR1LAP3 | |
| SCHEMBL6772330 | 0.67 | FDPS (0.42) | FDPSGRM4GABBR2GABBR1LMNA | |
| SCHEMBL3889337 | 0.65 | GABBR2 (0.39) | FDPSGRM4GABBR2GABBR1LMNA | |
| SCHEMBL11421891 | 0.65 | GABBR2 (0.39) | FDPSGRM4GABBR2GABBR1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802919-A4 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL INC (US) | 1999-08-18 | — | — | EP | disclosed |
| EP-0802919-A1 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995033757-A1 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1995-12-14 | — | — | WO | disclosed |