Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8332157 | 1.00 | ACHE (0.41) | ACHEKCNH2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8997331 | 0.89 | ACHE (0.44) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8997349 | 0.89 | ACHE (0.44) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| Trifluoromethanesulfonic Acid SCHEMBL5705509 | 0.87 | ACHE (0.40) | ACHEKCNH2GPR3 | |
| Trifluoromethanesulfonic Acid SCHEMBL5705511 | 0.87 | ACHE (0.40) | ACHEKCNH2GPR3 | |
| Trifluoromethanesulfonic Acid SCHEMBL2996949 | 0.85 | ACHE (0.42) | ACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL5705540 | 0.84 | MAPT (0.39) | ACHEKCNH2HPGDHSD17B10 | |
| Trifluoromethanesulfonic Acid SCHEMBL38665301 | 0.84 | MAPT (0.39) | ACHEKCNH2HPGDHSD17B10 | |
| SCHEMBL9397404 | 0.84 | ACHE (0.53) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10695794 | 0.84 | LMNA (0.47) | ACHEKDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819119-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | disclosed |