Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997331 | 0.88 | ACHE (0.44) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8997349 | 0.88 | ACHE (0.44) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10695794 | 0.85 | LMNA (0.47) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8332152 | 0.84 | ACHE (0.41) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8332157 | 0.84 | ACHE (0.41) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6649021 | 0.83 | ACHE (0.52) | ACHEKDM4EALDH1A1HSD17B10EGFR | |
| SCHEMBL13433227 | 0.83 | KDM4E (0.40) | ACHEKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL31163696 | 0.82 | ACHE (0.50) | ACHE | |
| SCHEMBL8495949 | 0.82 | ACHE (0.50) | ACHE | |
| SCHEMBL7024186 | 0.82 | ACHE (0.50) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994028420-A1 | METHOD OF DETECTION OF BACTERIA | RHONE POULENC DIAGNOSTICS LTD (GB) | 1994-12-08 | — | — | WO | claimed |
| US-20100317877-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| EP-1651958-B1 | NOVEL CHEMILUMINESCENT COMPOUNDS AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2010-06-16 | — | — | EP | disclosed |
| US-7563902-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-7262306-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317877-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | ACHE 447/4885KDM4E 1890/4885MEN1 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.