SCHEMBL83322

SCHEMBL83322

NC(=O)/C=C/c1cccnc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.73
MAPT P10636 2/20 0.73
KDM4E B2RXH2 2/20 0.73
NPC1 O15118 2/20 0.73
JUN P05412 1/20 0.73
NFKB1 P19838 1/20 0.73
MAPK1 P28482 1/20 0.73
GPR55 Q9Y2T6 1/20 0.73
PFKFB3 Q16875 1/20 0.63
KMT2A Q03164 1/20 0.59
CYP1A1 P04798 9/20 0.56
CYP1A2 P05177 9/20 0.56
CYP1B1 Q16678 9/20 0.56
APAF1 O14727 1/20 0.56
POLB P06746 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
USP2 O75604 1/20 0.55
CYP11B1 P15538 1/20 0.55
CYP11B2 P19099 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83267 1.00 RAB9A (0.73) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL82827 0.88 RAB9A (0.62) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL5598852 0.85 MAPT (1.00) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL5598850 0.85 MAPT (1.00) RAB9AMAPTKDM4ENPC1JUN
Methyl Benzoate SCHEMBL30968567 0.83 ALDH1A1 (0.56) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL334614 0.83 RAB9A (0.76) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL29416684 0.83 RAB9A (0.76) RAB9AMAPTKDM4ENPC1JUN
Hydrochloric Acid SCHEMBL11971079 0.83 MAPT (0.96) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL334615 0.83 RAB9A (0.76) RAB9AMAPTKDM4ENPC1JUN
SCHEMBL755249 0.83 RAB9A (0.76) RAB9AMAPTKDM4ENPC1JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856735-B1 FUSED BICYCLIC HETEROCYCLES AS THERAPEUTIC AGENTS UNIV NEW YORK (US) 2023-09-06 EP claimed
WO-2023030170-A1 PROTEIN DEGRADATION COMPOUND BASED ON NAMPT TARGET PROTEIN AND APPLICATION THEREOF 标新生物医药科技(上海)有限公司 2023-03-09 WO claimed
EP-3856735-A1 FUSED BICYCLIC HETEROCYCLES AS THEREAPEUTIC AGENTS New York University (US) 2021-08-04 EP claimed
WO-2020073031-A1 FUSED BICYCLIC HETEROCYCLES AS THEREAPEUTIC AGENTS NEW YORK UNIVERSITY (US) 2020-04-09 WO claimed
CN-107130230-B The horizontal process of the electroless metal plating of substrate with ionic catalyst 罗门哈斯电子材料有限责任公司 2019-08-27 CN claimed
EP-3211123-B1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS ROHM & HAAS ELECT MAT (US) 2019-01-09 EP claimed
CN-107130230-A The horizontal process of the electroless metal plating of substrate with ionic catalyst 罗门哈斯电子材料有限责任公司 2017-09-05 CN claimed
US-20170251557-A1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS ROHM & HAAS ELECT MAT (US) 2017-08-31 US claimed
EP-3211123-A1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS Rohm and Haas Electronic Materials LLC (US) 2017-08-30 EP claimed
US-8591636-B2 Plating catalyst and method ROHM AND HAAS ELECTRONICS MATERIALS LLC (US) 2013-11-26 US claimed
JP-4607319-B2 2011-01-05 JP claimed
JP-4599062-B2 2010-12-15 JP claimed
JP-2005528361-A 2005-09-22 JP claimed
CN-1217943-C New use and novel N-azabicyclo-amide derivatives ASTRAZENECA AB (SE) 2005-09-07 CN claimed
EP-1487444-A1 USE OF PYRIDYL AMIDES AS INHIBITORS OF ANGIOGENESIS Fujisawa Deutschland GmbH (DE) 2004-12-22 EP claimed
WO-2003080054-A1 USE OF PYRIDYL AMIDES AS INHIBITORS OF ANGIOGENESIS FUJISAWA DEUTSCHLAND GMBH (DE) 2003-10-02 WO claimed
CN-1423651-A Novel use and novel N-azabicyclo-amide derivatives ASTRAZENECA AB (SE) 2003-06-11 CN claimed
JP-2002512190-A 2002-04-23 JP claimed
EP-1079832-A1 USE OF VITAMIN PP COMPOUNDS Klinge Pharma GmbH (DE) 2001-03-07 EP claimed
WO-1999053920-A1 USE OF VITAMIN PP COMPOUNDS KLINGE PHARMA GMBH (DE) 1999-10-28 WO claimed