Methyl Benzoate

Methyl Benzoate

SCHEMBL30968567

COC(=O)c1ccccc1.NC(=O)C=Cc1cccnc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
CYP1A1 P04798 9/20 0.53
CYP1A2 P05177 9/20 0.53
CYP1B1 Q16678 9/20 0.53
CYP3A4 P08684 4/20 0.53
CYP2D6 P10635 4/20 0.53
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.52
RAB9A P51151 2/20 0.52
KDM4E B2RXH2 1/20 0.52
NPC1 O15118 1/20 0.52
JUN P05412 1/20 0.52
NFKB1 P19838 1/20 0.52
MAPK1 P28482 1/20 0.52
GPR55 Q9Y2T6 1/20 0.52
PFKFB3 Q16875 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TSHR P16473 1/20 0.49
USP2 O75604 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Benzoate SCHEMBL29258696 0.85 TSHR (0.53) ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4
SCHEMBL83267 0.83 RAB9A (0.73) CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6
SCHEMBL83322 0.83 RAB9A (0.73) CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6
SCHEMBL8996130 0.81 ALDH1A1 (0.61) ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4
SCHEMBL8996089 0.81 ALDH1A1 (0.61) ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4
SCHEMBL8996085 0.81 ALDH1A1 (0.61) ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4
Methyl Benzoate SCHEMBL28765090 0.79 ALDH1A1 (0.73) ALDH1A1LMNAMAPTTSHRKMT2A
SCHEMBL29496403 0.79 ALDH1A1 (0.62) ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4
SCHEMBL22887482 0.79 ALDH1A1 (0.62) ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4
SCHEMBL28161757 0.77 HDAC1 (0.73) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239885-A Synthesis method of cidamine 常州合全药业有限公司 2024-06-25 CN claimed
CN-118239885-A Synthesis method of cidamine 常州合全药业有限公司 2024-06-25 CN disclosed