Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.73 |
| ▸ | DRD2 | P14416 | 8/20 | 0.73 |
| ▸ | HTR2A | P28223 | 3/20 | 0.73 |
| ▸ | HTR7 | P34969 | 3/20 | 0.73 |
| ▸ | HTR6 | P50406 | 3/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.61 |
| ▸ | DRD3 | P35462 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332830 | 0.93 | HTR1A (0.66) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9023923 | 0.83 | HTR1A (0.66) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9760092 | 0.81 | HTR1A (0.62) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11676714 | 0.81 | HTR1A (0.64) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9759010 | 0.80 | HTR1A (0.64) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL8577935 | 0.80 | DRD2 (0.72) | HTR1ADRD2HTR2AHTR7ADRA1A | |
| SCHEMBL11679210 | 0.79 | LMNA (0.66) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6526368 | 0.79 | DRD2 (0.85) | HTR1ADRD2HTR2AHTR7ADRA1A | |
| SCHEMBL9759563 | 0.79 | HTR1A (0.71) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL11676693 | 0.79 | DRD2 (0.60) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075308-A | Method for treating urinary obstruction | HITACHI CHEMICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |