Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273613 | 0.84 | ALOX5 (0.38) | TP53MAPTALOX5TGM2TYR | |
| SCHEMBL6184354 | 0.84 | AHR (0.40) | TP53MAPTCES1ALOX5TGM2 | |
| SCHEMBL8333850 | 0.82 | ALOX5 (0.62) | MAPTLMNAALOX5TXNRD1TXNRD3 | |
| SCHEMBL6256089 | 0.81 | ABL1 (0.41) | CHEK1 | |
| SCHEMBL6272881 | 0.80 | ABL1 (0.38) | MAPTLMNAALOX5TYR | |
| SCHEMBL8321281 | 0.78 | ALOX5 (0.65) | TP53MAPTLMNAALOX5 | |
| SCHEMBL172370 | 0.78 | LMNA (0.58) | TP53MAPTLMNACES1CHEK1 | |
| SCHEMBL6274420 | 0.77 | ALOX5 (0.42) | TP53MAPTALOX5TYRTXNRD1 | |
| SCHEMBL6267336 | 0.77 | ABL1 (0.48) | MAPTLMNAALOX5TYR | |
| SCHEMBL6270867 | 0.75 | SMN1; SMN2 (0.40) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033437-A1 | DIBENZOXAZEPINE | BAYER HEALTHCARE AG (DE) | 2004-04-22 | — | — | WO | disclosed |