Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | RARG | P13631 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330182 | 0.91 | RARA (0.47) | RARBRARARARGSMN1; SMN2 | |
| SCHEMBL8327517 | 0.78 | RARA (0.40) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL1140826 | 0.77 | RARB (0.60) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL8331248 | 0.75 | RARB (0.38) | RARBRARARARG | |
| SCHEMBL14384928 | 0.73 | RARB (0.53) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL726359 | 0.73 | RARA (0.60) | RARBRARARARG | |
| SCHEMBL6592216 | 0.72 | RARA (0.40) | RARBRARARARGSMN1; SMN2 | |
| SCHEMBL8329653 | 0.72 | RARA (0.37) | RARBRARARARGRAB9A | |
| SCHEMBL8328688 | 0.70 | RARA (0.52) | RARBRARARARG | |
| SCHEMBL8329461 | 0.70 | RARA (0.49) | RARBRARARARGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |