SCHEMBL833342

SCHEMBL833342

Cc1ccc2c(N)c(C)ccc2c1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
LMNA P02545 2/20 0.58
KDM4E B2RXH2 1/20 0.58
GAA P10253 1/20 0.58
HPGD P15428 1/20 0.58
HSD17B10 Q99714 1/20 0.58
POLB P06746 1/20 0.52
CD44 P16070 1/20 0.46
NOS3 P29474 2/20 0.42
NOS2 P35228 2/20 0.42
MAPT P10636 3/20 0.41
CYP1A2 P05177 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
CASP1 P29466 2/20 0.39
CYP3A4 P08684 4/20 0.38
TSHR P16473 3/20 0.38
TP53 P04637 1/20 0.38
NOS1 P29475 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3846386 0.83 ALDH1A1 (0.59) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL409314 0.82 POLB (0.61) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL24809340 0.79 ALDH1A1 (0.42) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL16194625 0.79 HPRT1 (0.58) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL3344492 0.79 NOS3 (0.48) ALDH1A1LMNAKDM4EGAAHPGD
Hydrochloric Acid SCHEMBL8125648 0.79 POLB (0.58) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL3645079 0.76 LMNA (0.46) ALDH1A1LMNAKDM4EGAAHPGD
Methyl Alcohol SCHEMBL7119741 0.76 POLB (0.55) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL8394412 0.75 LMNA (1.00) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL3341729 0.74 GAA (0.42) ALDH1A1LMNAKDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
CN-111433683-B Toner for developing electrostatic image and method for producing the same 日本瑞翁株式会社 2023-11-24 CN disclosed
EP-3623870-B1 IMAGE FORMING APPARATUS AND TONER SET RICOH CO LTD (JP) 2022-05-04 EP disclosed
US-11281117-B2 Toner for electrostatic-image development and method for manufacturing same ZEON CORPORATION (JP) 2022-03-22 US disclosed
EP-3418811-B1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD FOR MANUFACTURING TONER RICOH CO LTD (JP) 2021-07-28 EP disclosed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-10895816-B2 Image forming apparatus and toner set RICOH COMPANY, LTD. (JP) 2021-01-19 US disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
US-20200348609-A1 TONER FOR ELECTROSTATIC-IMAGE DEVELOPMENT AND METHOD FOR MANUFACTURING SAME ZEON CORPORATION (JP) 2020-11-05 US disclosed
CN-111433683-A Toner for developing electrostatic image and method for producing the same 日本瑞翁株式会社 2020-07-17 CN disclosed
EP-0376674-A1 Spray urethane elastomer MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-04 EP disclosed
EP-0219709-B1 POLYMETHYLENE POLYPHENYLAMINE MODIFIED DIAMINE CHAIN EXTENDERS AND POLYUREA ELASTOMERS THEREFROM THE DOW CHEMICAL COMPANY (US) 1989-11-23 EP disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0075130-B1 IMPROVED REACTION INJECTION MOLDING PROCESS THE DOW CHEMICAL COMPANY (US) 1986-09-17 EP disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed