Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 15/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070066 | 0.89 | ADK (0.79) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL8331350 | 0.88 | ADK (0.69) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL6236072 | 0.88 | ADK (0.69) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL8331212 | 0.88 | ADK (0.71) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL8331313 | 0.86 | ADK (0.81) | ADK | |
| SCHEMBL8332977 | 0.85 | ADORA3 (0.69) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL17800859 | 0.84 | ADK (0.80) | ADK | |
| SCHEMBL8974980 | 0.83 | ADK (0.71) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL8332893 | 0.83 | ADK (1.00) | ADK | |
| SCHEMBL8330336 | 0.82 | ADK (0.89) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684953-A4 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. | GENSIA INC (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0684953-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018215-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |