Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338912 | 0.86 | RXRA (0.41) | RARARARBRARGRAB9AKDM4E | |
| SCHEMBL8179509 | 0.86 | MAPT (0.46) | FLT3RAB9AKDM4EPOLBGAA | |
| SCHEMBL31045057 | 0.84 | FLT3 (0.41) | FLT3RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL20668057 | 0.84 | LMNA (0.50) | FLT3RAB9AKDM4EPOLBHTT | |
| SCHEMBL8338691 | 0.83 | SELE (0.45) | KDM4EMEN1ALDH1A1KMT2ARXRA | |
| SCHEMBL31044906 | 0.82 | FLT3 (0.53) | FLT3RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL8340672 | 0.81 | BRD4 (0.46) | RARARARBRARGPPARGRAB9A | |
| SCHEMBL8335829 | 0.81 | RXRA (0.40) | RARARARBRARGRORCRAB9A | |
| SCHEMBL8336344 | 0.80 | MEN1 (0.39) | RARARARBRARGRAB9AKDM4E | |
| SCHEMBL31044805 | 0.80 | KDM4E (0.40) | FLT3RAB9AKDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948911-A | Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives | CELL PATHWAYS, INC. (US) | 1999-09-07 | — | — | US | disclosed |