Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | CASP3 | P42574 | 2/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.65 |
| ▸ | RELA | Q04206 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30642229 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL833508 | 0.87 | ALDH1A1 (0.77) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL1171437 | 0.83 | NPC1 (0.82) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL27991181 | 0.83 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL4328218 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL594033 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL1541190 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL2711230 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL762631 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL16061454 | 0.80 | MAPT (0.74) | ALDH1A1TDP1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119606958-B | Composition containing pyruvate and preparation method and application thereof | 江苏长泰药业股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119606958-A | Composition containing pyruvate and preparation method and application thereof | 江苏长泰药业股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | claimed |
| CN-105384693-B | Compound, its synthetic method and the purposes of the structure of bisazo containing benzoxazole ring | 盐城工学院 | 2018-11-09 | — | — | CN | claimed |
| CN-105384693-A | Compound containing benzoxazole ring bis(azo) structure, synthetic method for compound and use of compound | YANCHENG INST TECHNOLOGY | 2016-03-09 | — | — | CN | claimed |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-05-30 | — | — | US | claimed |
| CN-119606958-B | Composition containing pyruvate and preparation method and application thereof | 江苏长泰药业股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119606958-A | Composition containing pyruvate and preparation method and application thereof | 江苏长泰药业股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-20240199562-A1 | UREA DERIVATIVES FOR TREATING UVEAL MELANOMA | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-06-20 | — | — | US | disclosed |
| CN-116589423-A | Phenylpropidium-urea compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2023-08-15 | — | — | CN | disclosed |
| CN-113271941-A | Urea derivatives for the treatment and/or prevention of cancer | 法国国家科学研究中心 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020079184-A2 | UREA DERIVATIVES FOR TREATING AND/OR PREVENTING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-04-23 | — | — | WO | disclosed |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | disclosed |
| EP-1594505-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | disclosed |
| WO-2004072101-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004072101-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |
| EP-0023889-B1 | IMINOISOINDOLINONE METAL COMPLEXES, PROCESS FOR THEIR MANUFACTURE, METHOD FOR PIGMENTING AN ORGANIC HIGH-MOLECULAR MATERIAL AND HIGH-MOLECULAR ORGANIC MATERIAL CONTAINING SUCH A METAL COMPLEX | CIBA-GEIGY AG (CH) | 1983-03-09 | — | — | EP | disclosed |
| EP-0023889-A1 | Iminoisoindolinone metal complexes, process for their manufacture, method for pigmenting an organic high-molecular material and high-molecular organic material containing such a metal complex | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |
| US-4065462-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | FLNB, BRI3BP, CCNI | ALDH1A1 1841/4885TDP1 3754/4885MAPT 3578/4885 |
| US-20240199562-A1 | UREA DERIVATIVES FOR TREATING UVEAL MELANOMA | UACA, SLC14A1, MITF | ALDH1A1 311/4885TDP1 2970/4885MAPT 409/4885 |
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | F7, SERPINE1, HABP2 | ALDH1A1 3767/4885TDP1 2997/4885MAPT 4322/4885 |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | FLNB, BRI3BP, CCNI | ALDH1A1 1841/4885TDP1 3754/4885MAPT 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.