SCHEMBL8336100

SCHEMBL8336100

CC(c1ccc(-c2ccc(F)cc2)cc1)c1c(O)c2ccccc2oc1=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VKORC1 Q9BQB6 2/20 0.74
NQO1 P15559 6/20 0.63
CYP2C9 P11712 6/20 0.60
CRHBP P24387 1/20 0.60
CASP7 P55210 1/20 0.60
CASP6 P55212 1/20 0.60
CRHR2 Q13324 1/20 0.60
HIF1A Q16665 1/20 0.60
TOP1 P11387 1/20 0.59
TOP2A P11388 1/20 0.57
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
RECQL P46063 1/20 0.53
GALK1 P51570 1/20 0.53
KMT2A Q03164 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469143 0.90 VKORC1 (0.78) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL8334288 0.89 VKORC1 (0.76) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL8336582 0.88 VKORC1 (0.74) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL8335689 0.87 VKORC1 (0.69) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL8334704 0.85 VKORC1 (0.70) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL7349603 0.85 VKORC1 (1.00) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL25198895 0.84 VKORC1 (0.58) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL7898320 0.83 NQO1 (0.86) NQO1CYP2C9CRHBPCASP7CASP6
SCHEMBL310481 0.82 VKORC1 (0.82) VKORC1NQO1CYP2C9CRHBPCASP7
SCHEMBL32659670 0.82 VKORC1 (0.82) VKORC1NQO1CYP2C9CRHBPCASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165242-A1 RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS LIPHATECH INC (FR) 2023-06-01 US disclosed
US-20230165242-A1 RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS LIPHATECH INC (FR) 2023-06-01 US disclosed
WO-2021224566-A1 RODENTICIDE BAIT AND METHOD FOR CONTROLLING HARMFUL TARGET RODENTS LIPHATECH (FR) 2021-11-11 WO disclosed
WO-1999001446-A1 NOVEL 4-HYDROXY-2H-1-(THIO)PYRAN-2-ONES DERIVATIVES AND THEIR USE AS RAT POISON LIPHATEC (FR) 1999-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165242-A1 RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS VDR, CYP2R1, CYP24A1 VKORC1 61/4885NQO1 3681/4885CYP2C9 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.