Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | KIF20A | O95235 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872853 | 0.81 | GPR84 (0.55) | GPR84KIF20AALDH1A1PBRM1ATM | |
| SCHEMBL10466726 | 0.77 | GPR84 (0.65) | GPR84KIF20AALDH1A1PBRM1ATM | |
| SCHEMBL17207498 | 0.75 | KIF20A (0.65) | GPR84KIF20AALDH1A1PBRM1ATM | |
| SCHEMBL26070596 | 0.75 | ALDH1A1 (0.57) | GPR84KIF20AALDH1A1PBRM1ATM | |
| SCHEMBL24651224 | 0.75 | GPR84 (0.61) | GPR84KIF20AALDH1A1PBRM1ATM | |
| SCHEMBL5653872 | 0.74 | GPR84 (0.64) | GPR84ALDH1A1PBRM1ATMMEN1 | |
| SCHEMBL274836 | 0.72 | KIF20A (0.79) | GPR84KIF20AAPPDYRK1AMEN1 | |
| SCHEMBL8575629 | 0.72 | KIF11 (0.45) | ALDH1A1PBRM1DYRK1AMEN1KMT2A | |
| SCHEMBL274837 | 0.72 | KIF20A (0.79) | GPR84KIF20AAPPDYRK1AMEN1 | |
| SCHEMBL28013222 | 0.72 | GPR84 (0.62) | GPR84ALDH1A1PBRM1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005058-A | Polydiacetylenes exhibiting extended wavelength absorption maxima | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 1999-12-21 | — | — | US | disclosed |