Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335367 | 0.81 | CFTR (0.50) | GPR35CFTRNOTUMMRGPRX4PDK2 | |
| SCHEMBL8112464 | 0.79 | CFTR (0.49) | GPR35CFTRNOTUMMAPK1MRGPRX4 | |
| SCHEMBL8428603 | 0.77 | GPR35 (0.37) | GPR35 | |
| SCHEMBL8428606 | 0.76 | SLC9A1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL8331420 | 0.76 | GPR35 (0.36) | GPR35 | |
| Hydrochloric Acid SCHEMBL8331426 | 0.75 | SLC9A1 (0.46) | — | |
| SCHEMBL8332067 | 0.74 | NOTUM (0.48) | GPR35CFTRNOTUMMRGPRX4PDK2 | |
| SCHEMBL2657595 | 0.74 | MRGPRX4 (0.51) | GPR35CFTRNOTUMMAPK1MRGPRX4 | |
| SCHEMBL8117858 | 0.72 | GPR35 (0.43) | GPR35CFTRNOTUMMRGPRX4GABRP | |
| SCHEMBL15934963 | 0.72 | PDE2A (0.41) | GPR35LMNAGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856574-A | ANTIISCHEMIC AGENTS; ANTIARRTHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |