Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112464 | 0.84 | CFTR (0.49) | CFTRGPR35NOTUMKDM4EPDK2 | |
| SCHEMBL27387385 | 0.83 | CFTR (0.53) | CFTRGPR35NOTUMKDM4ESOS1 | |
| SCHEMBL8337100 | 0.81 | GPR35 (0.48) | CFTRGPR35NOTUMKDM4EPDK2 | |
| SCHEMBL27887866 | 0.81 | RXRA (0.53) | GPR35NOTUMKDM4ERXRARXRB | |
| SCHEMBL16929808 | 0.80 | CFTR (0.58) | CFTRGPR35NOTUMKDM4ESOS1 | |
| SCHEMBL8332067 | 0.79 | NOTUM (0.48) | CFTRGPR35NOTUMKDM4EPDK2 | |
| SCHEMBL2657833 | 0.79 | ABL1 (0.47) | PDK2PTGS2ABL1PDK4CA12 | |
| SCHEMBL26120629 | 0.79 | PTGS2 (0.44) | PDK2PTGS2ABL1PDK4CA12 | |
| SCHEMBL2657595 | 0.79 | MRGPRX4 (0.51) | CFTRGPR35NOTUMKDM4EMRGPRX4 | |
| SCHEMBL3943371 | 0.78 | CFTR (0.64) | CFTRNOTUMKDM4EMRGPRX4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856574-A | ANTIISCHEMIC AGENTS; ANTIARRTHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |