SCHEMBL8337378

SCHEMBL8337378

CCCCOCc1ccc(OC)c(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.48
ATM Q13315 2/20 0.47
KDM4E B2RXH2 1/20 0.47
EPHX2 P34913 1/20 0.47
ALDH1A1 P00352 1/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
POLB P06746 1/20 0.45
CYP19A1 P11511 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27519166 0.95 CA2 (0.52) CA2L3MBTL1ATMKDM4EEPHX2
SCHEMBL8338754 0.91 CALM1 (0.52) CA2L3MBTL1KDM4EALDH1A1
SCHEMBL20956602 0.88 MEN1 (0.51) CA2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL7956564 0.86 CA2 (0.53) CA2L3MBTL1ATMKDM4EALDH1A1
SCHEMBL15259656 0.86 CALM1 (0.51) KDM4EALDH1A1
SCHEMBL258246 0.85 PTGS1 (0.56) L3MBTL1KDM4EEPHX2
SCHEMBL14763888 0.85 PTPN1 (0.54) CYP1A2CYP3A4
SCHEMBL29602123 0.85 PTPN1 (0.54) CYP1A2CYP3A4
SCHEMBL21402298 0.85 TUBB4A (0.52) CYP19A1CYP1A2CYP3A4
SCHEMBL117401 0.85 PTPN1 (0.54) CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11209320-A None JP disclosed
JP-H11209320-A VERATRYL ALCOHOL DERIVATIVE KAO CORP 1999-08-03 JP disclosed