SCHEMBL258246

SCHEMBL258246

CCCCOCc1ccc(OC(C)=O)c(OC)c1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.56
LTA4H P09960 2/20 0.55
TSHR P16473 1/20 0.48
TRPV1 Q8NER1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
PTGS2 P35354 1/20 0.45
EPHX2 P34913 1/20 0.45
NR3C1 P04150 1/20 0.45
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
JUN P05412 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258331 0.95 LTA4H (0.56) PTGS1LTA4HTSHRTRPV1EPHX2
SCHEMBL8337378 0.85 CA2 (0.53) L3MBTL1EPHX2KDM4E
Acetic Acid SCHEMBL29370510 0.81 GAA (0.55) TSHRTRPV1NFKB1
Acetic Acid SCHEMBL906422 0.81 ALDH1A1 (0.55) LTA4HTSHRTRPV1NFKB1
SCHEMBL27519166 0.81 CA2 (0.52) LTA4HL3MBTL1EPHX2KDM4E
SCHEMBL8338754 0.80 CALM1 (0.52) TSHRL3MBTL1KDM4ESMN1; SMN2
SCHEMBL4396133 0.80 S1PR2 (0.46) L3MBTL1EPHX2KDM4ESMN1; SMN2
SCHEMBL357406 0.80 PTGS1 (0.64) PTGS1LTA4HTSHRTRPV1NR3C1
Ethyl Acetate SCHEMBL20917769 0.80 CYP1A2 (0.50) LTA4HTSHRTRPV1KDM4ENFKB1
SCHEMBL2208675 0.80 LTA4H (0.56) PTGS1LTA4HTRPV1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250098726-A1 AEROSOLISABLE MATERIAL Nicoventures Trading Limited (GB) 2025-03-27 US claimed
EP-4463019-A1 AEROSOLISABLE MATERIAL Nicoventures Trading Limited (GB) 2024-11-20 EP claimed
WO-2023135408-A1 AEROSOLISABLE MATERIAL Nicoventures Trading Limited (GB) 2023-07-20 WO claimed
EP-3453364-B1 HEAT GENERATOR KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2022-08-24 EP claimed
EP-3348242-B1 HEATING COMPRESS KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2022-06-29 EP claimed
EP-3569671-B1 METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2022-06-22 EP claimed
US-11344488-B2 Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-05-31 US claimed
CN-110168038-B Methyl menthol derivative and cold sensate composition containing same 高砂香料工业株式会社 2022-05-27 CN claimed
US-11241331-B2 Heating compress KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) 2022-02-08 US claimed
US-11236042-B2 Methylmenthol derivative and cool-sensation imparter composition containing same TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-02-01 US claimed
US-20100093869-A1 SENSATION MASKING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) 2010-04-15 US claimed
US-20090208427-A1 Vanillin Acetals and Sensory Stimulant Composition Containing the Same TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-08-20 US claimed
EP-1912516-A2 SENSATION MASKING COMPOSITION Takasago International Corporation (USA) (US) 2008-04-23 EP claimed
EP-1902043-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME Takasago International Corporation (JP) 2008-03-26 EP claimed
EP-1885275-A1 TOPICAL WARMING COMPOSITION Takasago International Corporation (USA) (US) 2008-02-13 EP claimed
WO-2007022056-A2 SENSATION MASKING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) (US) 2007-02-22 WO claimed
US-20070036733-A1 Sensation masking composition TAKASAGO INTERNATIONAL CORP. (USA) (US) 2007-02-15 US claimed
WO-2007004740-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-01-11 WO claimed
WO-2006130710-A1 TOPICAL WARMING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-12-07 WO claimed
US-20060269500-A1 Topical warming composition TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-11-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070036733-A1 Sensation masking composition TRPA1, TRPV1, TRPM5 PTGS1 2275/4885LTA4H 251/4885TSHR 4026/4885
US-20100093869-A1 SENSATION MASKING COMPOSITION TRPA1, TRPV1, TRPM5 PTGS1 2275/4885LTA4H 251/4885TSHR 4026/4885
US-20060269500-A1 Topical warming composition CUTA, NACA, LSM14A PTGS1 1861/4885LTA4H 258/4885TSHR 3612/4885
US-11344488-B2 Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative CNR2, ADRB2, TRPA1 PTGS1 1200/4885LTA4H 2260/4885TSHR 1110/4885
US-20090208427-A1 Vanillin Acetals and Sensory Stimulant Composition Containing the Same TRPA1, TRPV1, TAS2R5 PTGS1 2364/4885LTA4H 1142/4885TSHR 4182/4885
US-11236042-B2 Methylmenthol derivative and cool-sensation imparter composition containing same TRPM8, TRPM4, TRPM2 PTGS1 1095/4885LTA4H 2669/4885TSHR 3992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.