Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337645 | 0.90 | KMT2A (0.47) | DDX3XKMT2AMEN1NPC1MAPT | |
| SCHEMBL8336155 | 0.85 | KMT2A (0.48) | DDX3XKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6723568 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6723186 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL17079601 | 0.79 | DDX3X (0.74) | DDX3XKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8338006 | 0.78 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL8334912 | 0.78 | KMT2A (0.53) | KMT2ANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6713855 | 0.77 | MAPT (0.56) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6723389 | 0.77 | MAPT (0.56) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6824922 | 0.75 | KMT2A (0.63) | KMT2APOLBPYGLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |