Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MYOC | Q99972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337404 | 0.90 | DDX3X (0.59) | KMT2ATSHRPYGLDDX3XMAPT | |
| SCHEMBL6723568 | 0.86 | ALDH1A1 (0.51) | KMT2ATSHRPYGLMAPTALDH1A1 | |
| SCHEMBL6723186 | 0.86 | ALDH1A1 (0.51) | KMT2ATSHRPYGLMAPTALDH1A1 | |
| SCHEMBL8338006 | 0.84 | KMT2A (0.54) | KMT2ATSHREPHX1PYGLMAPT | |
| SCHEMBL6723389 | 0.83 | MAPT (0.56) | KMT2ATSHRPYGLMAPTALDH1A1 | |
| SCHEMBL6713855 | 0.83 | MAPT (0.56) | KMT2ATSHRPYGLMAPTALDH1A1 | |
| SCHEMBL8334912 | 0.80 | KMT2A (0.53) | KMT2ATSHREPHX1PYGLALDH1A1 | |
| SCHEMBL8336155 | 0.80 | KMT2A (0.48) | KMT2ATSHRPYGLDDX3XSMN1; SMN2 | |
| SCHEMBL6824922 | 0.78 | KMT2A (0.63) | KMT2ATSHRPYGLTDP1 | |
| SCHEMBL16790895 | 0.77 | ALDH1A1 (0.62) | KMT2ADDX3XMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |