Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032715 | 0.87 | IKBKB (0.64) | TSHRCDC7TDP1HDAC2KMT2A | |
| SCHEMBL29771149 | 0.82 | L3MBTL1 (0.63) | TSHRTDP1KMT2AALDH1A1ALOX15 | |
| SCHEMBL4639633 | 0.82 | L3MBTL1 (0.63) | TSHRTDP1KMT2AALDH1A1ALOX15 | |
| SCHEMBL27940770 | 0.80 | TSHR (0.58) | TSHRCDC7TDP1KMT2AALDH1A1 | |
| SCHEMBL27889371 | 0.80 | TSHR (0.68) | TSHRTDP1HDAC2KMT2AALDH1A1 | |
| SCHEMBL28245589 | 0.78 | TSHR (0.81) | TSHRTDP1HDAC2KMT2AALDH1A1 | |
| SCHEMBL6541802 | 0.78 | ALOX15 (0.57) | TSHRPELI1TDP1HDAC2KMT2A | |
| SCHEMBL10992087 | 0.78 | CDC7 (0.50) | TSHRCDC7TDP1HDAC2KMT2A | |
| SCHEMBL28012071 | 0.78 | KMT2A (0.61) | TSHRCHUKTDP1KMT2AALDH1A1 | |
| SCHEMBL7256623 | 0.78 | BCAT2 (0.57) | TSHRCDC7TDP1HDAC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |