Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520190 | 0.77 | GAA (0.67) | GAAGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL16249736 | 0.76 | GABBR2 (0.61) | GAAGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL11228867 | 0.75 | GAA (0.52) | GAAGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL2386276 | 0.75 | GABBR2 (0.57) | GAAGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL8337797 | 0.73 | GRM8 (0.49) | GAALMNACYP2C9BLMCYP3A4 | |
| SCHEMBL2437666 | 0.73 | HSD17B10 (0.42) | GAALMNACYP2C9MEN1KMT2A | |
| SCHEMBL4129677 | 0.73 | AKR1C3 (0.47) | LMNACYP2C9MEN1KMT2ACYP3A4 | |
| SCHEMBL11229344 | 0.72 | GABBR2 (0.53) | GAAGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL272365 | 0.72 | GAA (0.50) | GAALMNACYP2C9MEN1KMT2A | |
| SCHEMBL3654833 | 0.71 | GAA (0.49) | GAAGABBR2GABBR1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |