Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 4/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032472 | 0.76 | GPR35 (0.58) | GRM8GRM4GPR35CYP1A2TSHR | |
| SCHEMBL2438044 | 0.76 | GRM8 (0.50) | GRM8GRM4GPR35CYP1A2TSHR | |
| SCHEMBL4142382 | 0.76 | GRM8 (0.50) | GRM8GRM4GPR35CYP1A2TSHR | |
| SCHEMBL1857061 | 0.75 | FNTA (0.58) | CYP1A2TSHRGAALMNAMAPT | |
| SCHEMBL5595045 | 0.75 | GPR35 (0.56) | GRM8GRM4GPR35CYP1A2TSHR | |
| SCHEMBL6267127 | 0.75 | GRM8 (0.46) | GRM8GRM4GPR35TSHRGAA | |
| SCHEMBL11703265 | 0.74 | GPR35 (0.44) | GPR35CYP1A2TSHRGAACASP6 | |
| SCHEMBL4319781 | 0.73 | GPR35 (0.55) | GRM8GRM4GPR35CYP1A2TSHR | |
| SCHEMBL8337703 | 0.73 | GAA (0.49) | CYP1A2TSHRGAALMNASMN1; SMN2 | |
| SCHEMBL4457398 | 0.73 | GPR35 (0.55) | GRM8GRM4GPR35CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |