SCHEMBL8337750

SCHEMBL8337750

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nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
CA4 P22748 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
MME P08473 4/20 0.37
SLC22A6 Q4U2R8 1/20 0.36
FNTA P49354 2/20 0.36
FNTB P49356 2/20 0.36
FOLH1 Q04609 1/20 0.35
RIMKLA Q8IXN7 1/20 0.35
NAALAD2 Q9Y3Q0 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6746101 1.00 CA2 (0.42) CA2CA4TDP1SMN1; SMN2MME
SCHEMBL13654785 0.88 CA2 (0.51) CA2CA4SMN1; SMN2MMEFNTA
SCHEMBL21954042 0.82 GABRR1 (0.33) CA2CA4TDP1SMN1; SMN2SLC22A6
SCHEMBL13020988 0.82 ALOX15 (0.34) CA2CA4TDP1SMN1; SMN2SLC22A6
SCHEMBL2918805 0.82 ECE1 (0.42) CA2FOLH1MAPT
SCHEMBL8028150 0.82 ECE1 (0.42) CA2FOLH1MAPT
SCHEMBL28337307 0.82 KDM4E (0.38) TDP1SMN1; SMN2MMEFNTAFNTB
SCHEMBL14989156 0.81 EPHX2 (0.37) CA2CA4MAPT
SCHEMBL9021257 0.80 SLC22A6 (0.32) CA2CA4TDP1SMN1; SMN2SLC22A6
SCHEMBL5088899 0.79 CA2 (0.41) CA2CA4TDP1SMN1; SMN2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105523833-A Special slow release water-soluble fertilizer for cotton, and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2016-04-27 CN claimed
CN-105503404-A Special organic water-soluble fertilizer for tea trees and preparation method of organic water-soluble fertilizer CHENGDU NEW KELI CHEM SCI CO 2016-04-20 CN claimed
CN-104671991-A Special slow-released water-soluble fertilizer for american ginseng and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2015-06-03 CN claimed
CN-104591879-A Special controlled-release water soluble fertilizer for grapes and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2015-05-06 CN claimed
CN-104557298-A Special sustained-release water-soluble fertilizer for potatoes and preparation method of fertilizer CHENGDU NEW KELI CHEM SCI CO 2015-04-29 CN claimed
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis SHENZHEN JINGTAI TECHNOLOGY CO., LTD. (CN) 2025-01-23 US disclosed
CN-118234705-A Aspartic acid derivative and application thereof in treatment of liver fibrosis, nonalcoholic hepatitis and other metabolic diseases 深圳利沃生物医药科技有限公司 2024-06-21 CN disclosed
WO-2023083291-A1 DERIVATIVE OF ASPARTIC ACID AND USE THEREOF IN TREATMENT OF METABOLIC DISEASES SUCH AS HEPATIC FIBROSIS AND NON-ALCOHOLIC HEPATITIS 深圳利沃生物医药科技有限公司 2023-05-19 WO disclosed
US-9663488-B2 Metalloenzyme inhibitor compounds VIAMET PHARMACEUTICALS, INC. (US) 2017-05-30 US disclosed
CN-106396869-A Yield-increase and quality-improvement water soluble fertilizer used for grapes 安徽省司尔特肥业股份有限公司 2017-02-15 CN disclosed
CN-105523833-A Special slow release water-soluble fertilizer for cotton, and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2016-04-27 CN disclosed
CN-105503404-A Special organic water-soluble fertilizer for tea trees and preparation method of organic water-soluble fertilizer CHENGDU NEW KELI CHEM SCI CO 2016-04-20 CN disclosed
US-5284828-A Hypotensive agents FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 1994-02-08 US disclosed
EP-0457195-A2 Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-11-21 EP disclosed
EP-0093128-B1 PROCESS FOR PREPARING OF METHYL ESTER OF ALPHA-ASPARTYL PHENYL ALANINE LABORATOIRES FOURNIER S.A. (FR) 1985-08-21 EP disclosed
EP-0055612-B1 RECOVERY OF L-PHENYLALANINE AND L-ASPARTIC ACID DURING PREPARATION OF ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER MONSANTO COMPANY (US) 1984-08-08 EP disclosed
EP-0093128-A1 PROCESS FOR PREPARING OF METHYL ESTER OF ALPHA-ASPARTYL PHENYL ALANINE. FOURNIER LAB SA (FR) 1983-11-09 EP disclosed
WO-1983001619-A1 METHOD FOR THE PREPARATION OF METHYL ESTER OF 'alpha'-ASPARTYL PHENYLALANINE GOURBAULT, MAURICE, JEAN 1983-05-11 WO disclosed
US-4348317-A Recovery of L-phenylalanine and L-aspartic acid during preparation of α-L-aspartyl-L-phenylalanine methyl ester MONSANTO COMPANY (US) 1982-09-07 US disclosed
EP-0055612-A1 Recovery of L-phenylalanine and L-aspartic acid during preparation of alpha-L-aspartyl-L-phenylalanine methyl ester MONSANTO COMPANY (US) 1982-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis GOT1, GOT2, GLS2 CA2 2121/4885CA4 1466/4885TDP1 2410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.