Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | LONP1 | P36776 | 2/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.48 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334677 | 0.83 | LONP1 (0.63) | CNR2CNR1LONP1PSMB11PSMA7 | |
| SCHEMBL8338450 | 0.76 | LMNA (0.55) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8338299 | 0.74 | SMYD3 (0.47) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8339627 | 0.74 | MAPK11 (0.44) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8337500 | 0.73 | CTSK (0.53) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8337093 | 0.73 | CYP1A2 (0.48) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8338430 | 0.72 | CNR2 (0.48) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8339320 | 0.72 | CNR2 (0.44) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8337739 | 0.72 | LMNA (0.54) | CNR2MAPK11MAPK14 | |
| SCHEMBL13735669 | 0.72 | MMP1 (0.47) | CNR2CNR1MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |