SCHEMBL8338486

SCHEMBL8338486

CCC(C)(C)c1cc(CCN)cc(C(C)(C)CC)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.41
BACE1 P56817 2/20 0.40
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 5/20 0.38
LMNA P02545 3/20 0.38
TSHR P16473 3/20 0.38
TAAR1 Q96RJ0 5/20 0.37
MAPK1 P28482 4/20 0.37
KDM4E B2RXH2 4/20 0.37
ADRA2A P08913 3/20 0.37
SLC6A2 P23975 3/20 0.37
DRD2 P14416 3/20 0.37
DRD1 P21728 3/20 0.37
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
TP53 P04637 2/20 0.37
ALOX15 P16050 2/20 0.37
HIF1A Q16665 2/20 0.37
HTR1A P08908 2/20 0.37
DRD4 P21917 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8340801 0.89 GAA (0.40) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL8339507 0.85 ALDH1A1 (0.40) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL3793958 0.82 GAA (0.57) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL2069834 0.81 MAPK1 (0.48) GAAKMT2AALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL8843697 0.81 GAA (0.56) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL9575261 0.80 ESR1 (0.36) GAAKMT2AMAPK1PTGS1CYP2C19
SCHEMBL11797622 0.80 HSPA5 (0.44) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL2070812 0.80 HSPA5 (0.53) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL2916130 0.80 TNKS2 (0.45) GAAKMT2AALDH1A1LMNATSHR
SCHEMBL10547624 0.80 PTGS2 (0.53) GAAKMT2AALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
WO-1993024938-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
WO-1993024935-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed