Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244044 | 0.87 | HSD17B10 (0.66) | HSD17B1HSD17B2HSD17B10MEN1KMT2A | |
| SCHEMBL8340975 | 0.87 | HSD17B10 (0.61) | HSD17B1HSD17B2HSD17B10MEN1KMT2A | |
| SCHEMBL699045 | 0.79 | HSD17B10 (0.81) | HSD17B10MEN1KMT2AALOX5CA12 | |
| SCHEMBL20147808 | 0.79 | MEN1 (0.62) | HSD17B1HSD17B2HSD17B10MEN1KMT2A | |
| SCHEMBL27559673 | 0.79 | MEN1 (0.53) | HSD17B1HSD17B2MEN1KMT2AUSP2 | |
| SCHEMBL9729361 | 0.79 | MEN1 (0.62) | HSD17B1HSD17B2MEN1KMT2AUSP2 | |
| SCHEMBL8335949 | 0.79 | GSTA1 (0.58) | HSD17B1HSD17B2HSD17B10MEN1KMT2A | |
| SCHEMBL7167628 | 0.78 | MEN1 (0.66) | HSD17B1HSD17B2MEN1KMT2AUSP2 | |
| SCHEMBL7713698 | 0.78 | FASN (0.59) | HSD17B1HSD17B2MEN1KMT2AUSP2 | |
| SCHEMBL22414007 | 0.78 | ATM (0.57) | HSD17B10MEN1KMT2ACYP2C8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |