SCHEMBL20147808

SCHEMBL20147808

O=C(c1ccccc1)c1cc(-c2ccc(O)cc2)ccc1-c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
LMNA P02545 1/20 0.62
MAPT P10636 1/20 0.62
RAB9A P51151 1/20 0.62
HSD17B10 Q99714 1/20 0.54
CYP2C9 P11712 2/20 0.53
CYP2C8 P10632 1/20 0.53
USP2 O75604 1/20 0.53
GAA P10253 1/20 0.53
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
MGLL Q99685 1/20 0.49
MMP3 P08254 2/20 0.47
MMP2 P08253 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LIG1 P18858 1/20 0.47
HSD17B1 P14061 1/20 0.47
HSD17B2 P37059 1/20 0.47
GSTA1 P08263 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244044 0.92 HSD17B10 (0.66) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL5959807 0.91 CYP2C9 (0.58) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL8340975 0.85 HSD17B10 (0.61) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL7167624 0.84 MAPT (0.63) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL13291426 0.83 MMP2 (0.51) MEN1KMT2ALMNAMAPTRAB9A
Acetic Acid SCHEMBL27418041 0.81 CYP2C9 (0.58) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL5506534 0.81 MEN1 (0.53) MEN1KMT2ACYP2C9CYP2C8ALDH1A1
SCHEMBL5701194 0.80 CYP2C8 (0.57) MEN1KMT2ALMNAMAPTRAB9A
Benzophenone SCHEMBL5719480 0.80 RAB9A (0.95) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL13291398 0.80 ITGB1 (0.50) MEN1KMT2ALMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134844-A1 Block Copolymer, Ion-Exchange Membrane And Method Of Preparing Block Copolymer KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2018-05-17 US disclosed