Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12543550 | 0.79 | GPR84 (0.35) | MGLL | |
| SCHEMBL19446211 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL11989420 | 0.76 | PARL (0.31) | — | |
| SCHEMBL13900968 | 0.76 | PARL (0.31) | — | |
| SCHEMBL12592622 | 0.74 | — | — | |
| SCHEMBL19956794 | 0.72 | — | — | |
| SCHEMBL14464255 | 0.71 | MGLL (0.36) | HTTALDH1A1PIK3CDPOLBMGLL | |
| SCHEMBL20999977 | 0.71 | PARL (0.38) | PIK3CDPOLB | |
| SCHEMBL9976427 | 0.71 | PARL (0.33) | PIK3CDPOLB | |
| SCHEMBL8148807 | 0.70 | MGLL (0.37) | HTTALDH1A1POLBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089925-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SEMAFORE PHARMACEUTICALS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |