Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334203 | 0.88 | GAA (0.34) | ALOX5 | |
| SCHEMBL8339611 | 0.82 | — | — | |
| SCHEMBL8334475 | 0.81 | CNR1 (0.33) | LMNA | |
| SCHEMBL8338337 | 0.80 | GAA (0.35) | ALOX5LMNA | |
| SCHEMBL8334276 | 0.77 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL8335851 | 0.70 | CNR2 (0.38) | — | |
| SCHEMBL8333490 | 0.70 | — | — | |
| SCHEMBL8389972 | 0.68 | ALDH1A1 (0.34) | LMNA | |
| SCHEMBL8337813 | 0.68 | TDP1 (0.39) | LMNA | |
| SCHEMBL8338863 | 0.67 | ALDH1A1 (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |