Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340810 | 0.76 | ADORA3 (0.47) | PNPADORA3 | |
| SCHEMBL8354948 | 0.68 | ADORA2A (0.33) | PNP | |
| SCHEMBL1992699 | 0.65 | ALDH1A1 (0.43) | ADORA3 | |
| SCHEMBL10518132 | 0.65 | ALDH1A1 (0.38) | PNP | |
| SCHEMBL1993927 | 0.64 | ADORA2A (0.41) | ADORA3 | |
| SCHEMBL5438523 | 0.63 | ALDH1A1 (0.41) | ADORA3JAK2JAK1 | |
| SCHEMBL9471538 | 0.63 | CRBN (0.39) | — | |
| SCHEMBL19181966 | 0.63 | PNP (0.48) | PNP | |
| SCHEMBL8338180 | 0.62 | ALDH1A1 (0.35) | PNPADORA3 | |
| SCHEMBL3845992 | 0.62 | RXFP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874578-A | Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process | BRISTOL-MYERS SQUIBB (US) | 1999-02-23 | — | — | US | disclosed |