Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 14/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340807 | 0.76 | PNP (0.33) | ADORA3PNP | |
| SCHEMBL10394332 | 0.68 | TYMP (0.54) | ADORA3HPRT1ALDH1A1 | |
| SCHEMBL11258920 | 0.68 | HPRT1 (0.69) | HPRT1PNP | |
| SCHEMBL9548816 | 0.68 | ALDH1A1 (0.61) | ADORA3HPRT1ALDH1A1LMNAALB | |
| SCHEMBL13058153 | 0.68 | ADORA3 (0.45) | ADORA3HPRT1ALDH1A1LMNAALB | |
| SCHEMBL30765431 | 0.67 | ADORA3 (0.44) | ADORA3HPRT1ALDH1A1LMNAALB | |
| SCHEMBL2679158 | 0.67 | ALDH1A1 (0.49) | ADORA3HPRT1ALDH1A1LMNAALB | |
| SCHEMBL13058159 | 0.66 | HPRT1 (0.50) | ADORA3HPRT1ALDH1A1LMNAALB | |
| SCHEMBL9308280 | 0.66 | ALDH1A1 (0.60) | ADORA3HPRT1ALDH1A1LMNAALB | |
| SCHEMBL1992701 | 0.66 | HPRT1 (0.54) | HPRT1ALDH1A1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874578-A | Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process | BRISTOL-MYERS SQUIBB (US) | 1999-02-23 | — | — | US | disclosed |