Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904938 | 0.75 | NPC1 (0.55) | MEN1KMT2AHRH4PDE3BPDE3A | |
| SCHEMBL20952966 | 0.70 | PDE3B (0.40) | NPSR1MEN1POLBKMT2APDE3B | |
| SCHEMBL7939160 | 0.68 | PDE3B (0.35) | MEN1POLBKMT2APDE3BPDE3A | |
| SCHEMBL23254194 | 0.67 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HRH4CYP2D6 | |
| SCHEMBL29546507 | 0.66 | NPSR1 (0.40) | NPSR1MEN1POLBKMT2ASLC6A2 | |
| SCHEMBL7932158 | 0.65 | ADRA2A (0.34) | POLBPDE3BPDE3ARAB9ASMN1; SMN2 | |
| SCHEMBL8344787 | 0.64 | CA1 (0.34) | MEN1POLBKMT2AHRH4HSD17B10 | |
| SCHEMBL12043688 | 0.64 | MAPT (0.33) | POLBPDE3BPDE3ANPC1RAB9A | |
| SCHEMBL10267287 | 0.64 | HTR5A (0.34) | PDE3BPDE3A | |
| SCHEMBL8340988 | 0.64 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |