Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043127 | 0.76 | PDE3B (0.34) | PDE3BPDE3ASIGMAR1NPC1HPGD | |
| SCHEMBL18417278 | 0.74 | GSK3A (0.40) | PDE3BPDE3ASIGMAR1NPC1HPGD | |
| SCHEMBL8340986 | 0.70 | NPSR1 (0.40) | PDE3BPDE3ANPC1HPGDRAB9A | |
| SCHEMBL18630355 | 0.67 | SIGMAR1 (0.35) | PDE3BPDE3ASIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL2717298 | 0.66 | PDE3B (0.42) | PDE3BPDE3ASIGMAR1GAA | |
| SCHEMBL256354 | 0.66 | SIGMAR1 (0.46) | SIGMAR1RAB9ASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL2437530 | 0.66 | — | — | |
| SCHEMBL2718109 | 0.65 | PDE3B (0.48) | PDE3BPDE3A | |
| SCHEMBL14908526 | 0.64 | SIGMAR1 (0.41) | PDE3BPDE3ASIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL10371070 | 0.63 | RIPK1 (0.35) | SIGMAR1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4002509-A1 | LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME | Samsung Electronics Co., Ltd. (KR) | 2022-05-25 | — | — | EP | disclosed |
| US-10273241-B2 | Cortistatin analogues and syntheses and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273241-B2 | Cortistatin analogues and syntheses and uses thereof | CDK19, CDK9, CDK1 | PDE3B 1037/4885PDE3A 1088/4885SIGMAR1 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.