Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236047 | 0.76 | ADRB1 (0.52) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL19852376 | 0.76 | CHRNB4 (0.57) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL27362287 | 0.75 | ADRB1 (0.50) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| Indole SCHEMBL10367462 | 0.74 | TRPA1 (0.45) | BPTFHTR2CSLC6A4KCNH2 | |
| SCHEMBL19852275 | 0.74 | CHRNB2 (0.62) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL19839303 | 0.74 | CHRNB2 (0.62) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL800968 | 0.74 | BPTF (0.53) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL12663143 | 0.74 | BPTF (0.53) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL4661349 | 0.71 | PLD1 (0.51) | DPP4TSHRCYP3A4CYP2D6MAPK1 | |
| SCHEMBL2330436 | 0.70 | BPTF (0.54) | BPTFSIGMAR1HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958923-A | TREATMENT OF NERVOUS SYSTEM DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |