Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296613 | 0.79 | TAAR1 (0.38) | LMNASMN1; SMN2ESR1ESR2TAAR1 | |
| SCHEMBL6296615 | 0.79 | TAAR1 (0.38) | LMNASMN1; SMN2ESR1ESR2TAAR1 | |
| SCHEMBL5880733 | 0.72 | RAB9A (0.33) | LMNASMN1; SMN2ESR1ESR2FAAH | |
| SCHEMBL6301600 | 0.72 | KDM4E (0.34) | LMNASMN1; SMN2ESR1KDM4EGRIN2B | |
| SCHEMBL5880858 | 0.71 | RAB9A (0.35) | LMNASMN1; SMN2ESR1ESR2FAAH | |
| SCHEMBL6301391 | 0.70 | KDM4E (0.33) | LMNASMN1; SMN2ESR1KDM4EGRIN2B | |
| SCHEMBL6297241 | 0.69 | LMNA (0.34) | LMNASMN1; SMN2ESR1KDM4EGRIN2B | |
| SCHEMBL6297058 | 0.69 | LMNA (0.36) | LMNAESR1ESR2KDM4EGRIN2B | |
| SCHEMBL6297773 | 0.69 | OPRM1 (0.33) | ALDH1A1MAPTGRIN2BSIGMAR1ADRB2 | |
| SCHEMBL6297134 | 0.69 | GRIN2B (0.35) | LMNASMN1; SMN2TAAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014210-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5,6-DIHYDRO-2H-PYRAN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |