Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28534276 | 0.87 | PSMD14 (0.51) | PAX8HTTPSMD14COPS5SLC6A2 | |
| SCHEMBL28527656 | 0.80 | PAX8 (0.55) | PAX8HTTSLC40A1METKDM4E | |
| SCHEMBL21005064 | 0.80 | PSMD14 (0.41) | PAX8HTTPSMD14COPS5SLC6A2 | |
| SCHEMBL10157939 | 0.80 | HTT (0.58) | HTTPSMD14COPS5SLC6A2SLC40A1 | |
| SCHEMBL28067774 | 0.78 | HTT (0.56) | PAX8HTTPSMD14COPS5SLC6A2 | |
| SCHEMBL10602531 | 0.77 | CYP1A2 (0.54) | PAX8KMT2ACYP1A2CYP2D6TSHR | |
| SCHEMBL16407670 | 0.75 | PSMD14 (0.53) | HTTPSMD14COPS5SLC6A2SLC40A1 | |
| SCHEMBL812451 | 0.74 | HTT (0.70) | HTTPSMD14COPS5SLC6A2SLC40A1 | |
| SCHEMBL1520610 | 0.74 | PAX8 (1.00) | PAX8HTTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL29448799 | 0.74 | PAX8 (0.51) | PAX8HTTMETKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108675999-B | Method for preparing 8- (9-sulfoxide-10-dihydrophenanthrene) quinoline compound under catalysis of copper acetate | 浙江农林大学暨阳学院 | 2021-03-16 | — | — | CN | disclosed |
| WO-2004007461-A1 | 8-HYDROXY QUINOLINE DERIVATIVES | PRANA BIOTECHNOLOGY LIMITED (AU) | 2004-01-22 | — | — | WO | disclosed |