Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16432828 | 0.69 | DRD2 (0.68) | DRD2DRD3ALDH1A1MAPTKDM4E | |
| SCHEMBL1568226 | 0.67 | ALDH1A1 (0.72) | ALDH1A1MAPTGAAHTTMEN1 | |
| SCHEMBL19028142 | 0.67 | TSHR (0.76) | GAAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29798002 | 0.66 | HSD17B10 (0.45) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL22663565 | 0.66 | HSD17B10 (0.45) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL17085933 | 0.66 | DRD2 (0.61) | DRD2DRD3ALDH1A1MAPTKDM4E | |
| SCHEMBL19623369 | 0.66 | ALDH1A1 (0.78) | ALDH1A1MAPTGAAHTTNPSR1 | |
| SCHEMBL22663431 | 0.66 | ALDH1A1 (0.43) | DRD2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL6665657 | 0.65 | ALDH1A1 (0.60) | DRD2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL14082493 | 0.65 | MMP13 (0.79) | ALDH1A1MAPTGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014389-A1 | 3,4-DIHYDROQUINOLIN-2-ONE, 5,6-FUSED OXAZIN-3-ONE, AND 5,6-FUSED THIAZIN-3-ONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |